Just a heads up here because I hit this both on my workstation and our test farm, but there was a feature added in 10.1.11 that recursively sets permissions on “%localappdata%\Thinkbox\Deadline10\pythonAPIs” when starting the Monitor or Deadline Command.
For me, I had 33 cached Python library folders in there and which added up to ~62 seconds every time I started my Monitor.
We’ll be fixing that for 10.1.14 but in the mean time if you’re waiting longer than you’d like try moving that folder after closing all of the Deadline applications.